El único máster en PNI clínica que cuenta con comité científico internacional propio

Chronic nonspecific low back pain (CNLBP) is a widely recognized condition worldwide. Its clinical management must be based on the best current evidence to achieve optimal outcomes, yet there is still a lack of consensus on its clinical approach. Objective: To evaluate the effectiveness of manual therapy (MT) on pain intensity, frequency, disability, and quality of life in adults with chronic nonspecific low back pain (CNLBP)

A multidisciplinary approach, including PNE, is recommended. Further research using standardized tools and diverse populations is needed to enhance the efficacy and generalizability of PNE interventions.

Through a comprehensive analysis of existing literature, we aim to shed light on the mechanisms underlying these interventions and their potential impact on disease progression and patient outcomes.

This meta-analysis highlights the role of metabolic dysfunction and chronic inflammation in the pathogenesis of FS. HbA1c and cholesterol were the most associated metabolic biomarkers, while IL-1β and TNF-α showed a strong link to inflammation and fibrosis.

This review explores the multifaceted role of the Warburg effect in type 2 diabetes and other metabolic and endocrine chronic disorders and examines the therapeutic potential of different interventions such as intermittent fasting, ketogenic diets, ketone supplements, and sodium/glucose co-transporter 2 inhibitors.

Stress is no stress when adaptive strategies or decision making eliminates their impact at time. Stress becomes distress, and therefore chronic irritation, when the challenging factor is long lasting and immunogenic. In this way it is the text choosing the disease (genetic and epigenetic susceptibility) and the context producing the conflict.

This review is the first study that has identified the metabolomic changes in different types of cancer and the use of metabolomic-based interventions in those patients.

Mitochondria play a key role in both health and disease. Their function is not limited to energy production but serves multiple mechanisms varying from iron and calcium homeostasis to the production of hormones and neurotransmitters, such as melatonin.

Psychoneuroimmunology is a rapidly advancing field that investigates immunological processes (at numerous levels of measurement) as risk factors, mechanisms, and sequelae of psychological phenomena.

The potential contribution of chronic inflammation to the development of neuropsychiatric disorders such as major depression has received increasing attention.

Humans and their gut bacteria have evolved multiple ways to communicate with and regulate one another. Psychological stress and depression can promote consumption of highly palatable foods, influencing which gut bacteria thrive.

Psychoneuroimmunology-based interventions are used to attenuated disease progression and/or side effects of pharmacological treatment.

Sleep has a critical role in promoting health. Research over the past decade has documented that sleep disturbance has a powerful influence on the risk of infectious disease, the occurrence and progression of several major medical illnesses including cardiovascular disease and cancer, and the incidence of depression.

Inflammation is the common link among the leading causes of death. Mechanistic studies have shown how various dietary components can modulate key pathways to inflammation including sympathetic activity.

Why are depressed people more likely to suffer heart attacks? Why do people with hostile worldviews have higher rates of metabolic syndrome and Type 2 diabetes?

Work in our laboratory has focused on the mechanisms by which cytokines can influence the brain and behavior in humans and non-human primates.